Status: question. Rule: atlas-profile-2.0.
4 linked publications; not a count of independent studies.
Missing appraisal does not mean no evidence exists. Inspect the full profile and source relationships in the interactive Atlas.
Historical grade: EXPERT-CONSENSUS (retained from 22 September 2026; not a completed profile 2.0 assessment).
A large fraction of imaging-outcome evidence predates CNS5; correlations may be miscalibrated to obsolete tumor classes, silently distorting current practice.
CNS5 improves biological precision but legacy imaging cohorts are rarely re-annotated and re-tested.
Re-annotate legacy imaging cohorts to CNS5 molecular entities; re-estimate imaging-biomarker associations; report which survive.
This question comes from selected literature. Confirm that the gap remains open with a current search and mentor review.
This is an educational research resource from Resonant Labs, not clinical advice. Atlas assessments are heuristic, not probabilities or formal GRADE ratings. Findings are summarized from the literature and may change as the field evolves.