Status: question. Rule: atlas-profile-2.0.
5 linked publications; not a count of independent studies.
Missing appraisal does not mean no evidence exists. Inspect the full profile and source relationships in the interactive Atlas.
Historical grade: WEAK (retained from 22 September 2026; not a completed profile 2.0 assessment).
The hand-crafted radiomics enterprise rests on reproducibility that is largely retrospective; if signal cannot survive prospective standardization it will not translate.
IBSI/ComBat make features poolable, but harmonization can remove real biological variance along with batch effect.
Prospective standardized-acquisition study comparing pre-specified radiomic signatures with and without harmonization against outcome; quantify biology-vs-batch tradeoff.
This question comes from selected literature. Confirm that the gap remains open with a current search and mentor review.
This is an educational research resource from Resonant Labs, not clinical advice. Atlas assessments are heuristic, not probabilities or formal GRADE ratings. Findings are summarized from the literature and may change as the field evolves.