Evidence grade: WEAK — Supported only by weak or preliminary evidence.
computed from the encoded evidence by the Atlas grading rule.
IBSI standardization and ComBat harmonization make radiomic features reproducible and poolable
Features remain sensitive to voxel resampling, segmentation, scanner, and software; harmonization can remove real biological signal along with batch effect
Reproducibility crisis undermines translation of the entire hand-crafted radiomics enterprise
This is an educational research resource from Resonant Labs, not clinical advice. Evidence grades and controversies are summarized from the literature and may change as the field evolves.