Controversy

Is MRI sensitive enough to reliably detect perineural tumor spread (PNS) for treatment planning?

Evidence profile

Status: awaiting_review. Rule: atlas-profile-2.0.

4 linked publications; not a count of independent studies.

Missing appraisal does not mean no evidence exists. Inspect the full profile and source relationships in the interactive Atlas.

Historical grade: WEAK (retained from 22 September 2026; not a completed profile 2.0 assessment).

Position A

Dedicated MRI depicts named-nerve PNS (V/VII) and changes radiation volumes and prognosis

Position B

Sensitivity is protocol- and reader-dependent, early/skip PNS is missed, and no standardized reporting exists

Clinical stakes

Missed PNS undertreats and worsens recurrence; over-call expands radiation fields unnecessarily.

Open in the interactive atlas →

About this page

Curated and maintained by Resonant Labs. Editorial lead: E. Brooke Schrickel, M.D. Claims are synthesized from the cited literature and graded per the Atlas methodology (about the Atlas). Page generated 2026-10-02. This is not a new clinical review date.

This is an educational research resource from Resonant Labs, not clinical advice. Atlas assessments are heuristic, not probabilities or formal GRADE ratings. Findings are summarized from the literature and may change as the field evolves.