Controversy

Is MRI sensitive enough to reliably detect perineural tumor spread (PNS) for treatment planning?

Evidence grade: WEAK — Supported only by weak or preliminary evidence.

computed from the encoded evidence by the Atlas grading rule.

Position A

Dedicated MRI depicts named-nerve PNS (V/VII) and changes radiation volumes and prognosis

Position B

Sensitivity is protocol- and reader-dependent, early/skip PNS is missed, and no standardized reporting exists

Clinical stakes

Missed PNS undertreats and worsens recurrence; over-call expands radiation fields unnecessarily.

Open in the interactive atlas →

About this page

Curated and maintained by Resonant Labs. Reviewed by Claims are synthesized from the cited literature and graded per the Atlas methodology (about the Atlas). Last updated 2026-07-14.

This is an educational research resource from Resonant Labs, not clinical advice. Evidence grades and controversies are summarized from the literature and may change as the field evolves.