Evidence grade: WEAK — Supported only by weak or preliminary evidence.
computed from the encoded evidence by the Atlas grading rule.
Defined CT/MRI criteria and, increasingly, AI models detect ENE with clinically useful accuracy and prognostic value
Diagnostic performance is moderate with limited reproducibility; consensus criteria are only now emerging and AI models are largely internally validated
Imaging-called ENE upstages disease and shifts patients toward chemoradiation/surgery; false positives overtreat.
This is an educational research resource from Resonant Labs, not clinical advice. Evidence grades and controversies are summarized from the literature and may change as the field evolves.