Status: awaiting_review. Rule: atlas-profile-2.0.
7 linked publications; not a count of independent studies.
Missing appraisal does not mean no evidence exists. Inspect the full profile and source relationships in the interactive Atlas.
Historical grade: WEAK (retained from 22 September 2026; not a completed profile 2.0 assessment).
Multiple ML/DL models report AUCs 0.7-0.9 for MGMT prediction on multiparametric MRI
Well-designed studies conclude MRI cannot reliably predict MGMT; BraTS-MGMT-style tasks show near-chance external performance; positive results attributed to leakage/overfitting
MGMT governs temozolomide benefit; a false imaging surrogate could misdirect therapy or trial stratification
This is an educational research resource from Resonant Labs, not clinical advice. Atlas assessments are heuristic, not probabilities or formal GRADE ratings. Findings are summarized from the literature and may change as the field evolves.